产品货号：
Z15900
中文名称：
DNA-PKcs/PRKDC抗体
英文名称：
Anti-DNA-PKcs/PRKDC Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-DNA-PKcs/PRKDC Antibody |
| 指标别名 | DNA PK catalytic subunit;DNAPK;DNA-PKcs;DNPK1;HYRC;HYRC1;p350;p460;PRKDC;XRCC7 |
| 克隆性 | Polyclonal |
| 检验物种 | mouse,rat |
| 应用范围 | IHC |
| 基因名称 | PRKDC |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence at the N-terminus of human DNA PKcs(328-346aa AKNAEMHKNKLQYFMEQFY). |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | PRKDC(Protein Kinase DNA-Activated Catalytic Subunit),also called DNAPK,HYRC1,p350 or DNPK1,is an enzyme that in humans is encoded by the PRKDC gene.DNA-PKcs belongs to the phosphatidylinositol 3-kinase-related kinase protein family.Satoh et al.(1997) mapped the MCM4 gene to 8q11.2 by FISH.Based on the close proximity of the PRKDC and MCM4 genes,it was assumed that the PRKDC gene also maps to this location.Anderson and Lees-Miller(1992) noted that DNA-PK had been shown in vitro to phosphorylate several transcription factors,suggesting that it functions in cell homeostasis by modulating transcription.Daniel et al.(1999) demonstrated that the PRKDC protein participates in retroviral DNA integration,which is catalyzed by the viral protein integrase. |
| Uniprot ID | P78527 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1866) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | protein kinase,DNA-activated,catalytic polypeptide |
| 蛋白名全称 | DNA-dependent protein kinase catalytic subunit |
| 推荐稀释比 | Immunohistochemistry in paraffin section (IHC) 1:50～400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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